Analysis of Genomes

The genome of an organism is the whole hereditary information of an organism that is encoded in the DNA. Genomes are more than the sum of an organism’s genes and have traits that may be measured and studied without reference to the details of any particular genes and their products.

The study of the global properties of genomes of related organisms is usually referred to as genomics, which distinguishes it from genetics which generally studies the properties of single genes or groups of genes.

It examines the structure and functions of genes and chromosomes: what they consist of, how they work, how they are regulated and how they may change. The basic molecular processes such as gene structure, transcription and translation, gene regulation, DNA replication, mutation, DNA repair and transposition, etc., are also described in detail. The present volume is an introduction to the fundamental concepts and methodologies of genomic analysis and their application in the context of post-genomic research. This book contains:

—INTRODUCTION TO GENOMICS
—GENES AND CHROMOSOMES
—DNA CHEMISTRY AND BIOLOGY
—DNA AND CHROMOSOMES
—DNA STRUCTURE AND MANIPULATION
—DNA MICROARRAYS
—NATURAL SELECTION AND VARIATION
—MOLECULAR TECHNIQUES
—FLUORESCENCE
—CHROMOSOMAL ANOMALIES
—GENE NETWORK RECONSTRUCTION
—GENETIC AND PHYSICAL MAPS OF THE GENOME

The book will be a good reference guide for students, teachers and scientists in the fields of biology and genetic engineering.